What We Do

Massachusetts General Brigham (MGB) Clinical Trials Office

The Clinical Trials Office provides contracting, budgeting and CTMS services to our member-hospital investigators and their industry sponsors conducting Phase I-IV clinical trials.

CTO Agreements Team

New Contracts

The CTO Agreements Team is available to draft, negotiate and execute a variety of clinical research agreement types. These include:

  • Company Initiated and PI Initiated Clinical Trial Agreements
  • Support Agreements including:
    • Core Laboratory
    • Study Chairperson and Steering Committee Agreements
    • Equipment/software loans
    • Free drug/device donations
  • Confidentiality Agreements
  • Data Usage Agreements
  • Master Clinical Trial/Services Agreements
  • Agreement Amendments

Our team of Agreement Associates hold JD degrees.

CTO Finance Team

Financial Services
The CTO Finance Team is available to assist investigators with:
  • Budget preparation and negotiation
  • Payment Schedules
  • Fund set up
  • MCA analysis
  • Consultation
  • Potential subject population analyses utilizing the RPDR database

CTO CTMS Team

Trial Management

The CTO CTMS Team manages a series of clinical trial support systems:

  • MGB OnCore Clinical Trial Management System
    This system is available to support non-oncology, industry-sponsored clinical trials within MGB, with a focus on subject visit tracking and invoicing.
  • Advarra Payments
    This system offers a reloadable credit card-based system for making stipend payments to clinical trial subjects